NMS-007 - Drug Design and Optimisation of the Fibroblast Growth Factor Receptor Type 4(FGFR4)

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: NMS-007
• By: SHOEMAKE, Claire
• Co-author(s): Ms Martina Buhagiar (University Of Malta, Msida, Malta)
  Dr Claire Shoemake (University Of Malta, Msida, Malta)
  
• Abstract:

  Introduction: Colorectal cancer remains one of the most aggressive and treatment-resistant cancers. Chemo-resistance is one of the greatest limitations to the efficacy of existing pharmacotherapy. Literature identified the FGFR4 receptor and its ligand FGF19 as drivers for cancer growth and chemoresistance. FGR4 inhibition could therefore result..

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