DDM-022 - Amorphous solid dispersions of Felodipine with various molecular weights of PEG's for dissolution enhancement using organic solvent-free supercritical CO2 processing: A green and sustainable technology

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: DDM-022
• By: KOLIPAKA, Siva Satyanarayana (University of Greenwich, United Kingdom)
• Co-author(s): Mr Siva Satyanarayana Kolipaka (University of Greenwich, Gillingham, United Kingdom)
  Dr. Laura Andrade Junqueira (Delta Pharmaceutics Ltd, Chatham, United Kingdom)
  Dr. Vivek Trivedi (University of Kent, Chatham, United Kingdom)
  Dr. Dennis Douroumis (University of Greenwich, Gillingham, United Kingdom)
  Danai Theodoridou (University of Greenwich, Gillingham, United Kingdom)
  Lanya Ghafffoori (University of Greenwich, Gillingham, United Kingdom)
  
• Abstract:

  Introduction
  Solid dispersions (SDs) are one of the unique techniques used to improve the solubility. SDs contain at least two distinct components, usually a hydrophilic matrix and a hydrophobic drug. CO₂ exists as a critical fluid at critical temperature (Tc) 31.1°C and critical pressure (Pc) 7.38 MPa. This work aims to study the potential of..

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