NMS-004 - Drug design and optimisation at the Pregnane X receptor

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: NMS-004
• By: SHOEMAKE, Claire
• Co-author(s): Ms Maria Martina Cutajar (University Of Malta, Msida, Malta)
  Dr Claire Shoemake (University Of Malta, Msida, Malta)
  
• Abstract:

  Introduction
  Drug-drug interactions, prevalent in elderly patients with polypharmacy, reduce pharmacotherapeutic efficacy or cause adverse effects, which may lead to morbidity and hospitalisation. The discovery that antagonism of the Pregnane X Receptor (PXR) reduced these interactions made this receptor a significantly important target from a..

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