PPM-009 - Causal relationship between inherited immune traits and cisplatin-induced ototoxicity in cancer patients: A bidirectional two-sample Mendelian randomization study

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: PPM-009
• By: ZHENG, Yang (Chongqing University of Medical Sciences Second Affiliated Hospital, China)
• Co-author(s): Mr Yang Zheng (Chongqing University of Medical Sciences Second Affiliated Hospital, Chongqing, China)
  Prof Di Li (Chongqing University of Medical Sciences Second Affiliated Hospital, Chongqing, China)
  
• Abstract:

  Introduction: Cisplatin is an effective chemotherapeutic agent for solid tumors, but its clinical use is limited by dose-dependent ototoxicity. Current challenges include the lack of reliable biomarkers for predicting ototoxicity and effective prevention or treatment strategies. Previous researches have linked genetic features, such as single..

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