PPM-015 - Exposure to multiple drugs with actionable pharmacogenetic biomarkers among older adults in China: A retrospective analysis

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: PPM-015
• By: HU, Xiaowen (Peking University Health Science Centre, China)
• Co-author(s): Ms Xiaowen Hu (Peking University Health Science Centre, Beijing, China)
  Ms Yuxuan Zhao (Peking University Health Science Centre, Beijing, China / Peking Union Medical College Hospital, Beijing, China)
  Ms Xue Wang (Peking University Health Science Centre, Beijing, China)
  Mr Gengchen Wang (Peking University Health Science Centre, Beijing, China)
  Ms Xinyi Zhang (Peking University Health Science Centre, Beijing, China)
  Ms Wenliang Dong (Peking University Health Science Centre, Beijing, China)
  Prof Luwen Shi (Peking University Health Science Centre, Beijing, China)
  Prof Christine Y Lu (Harvard Medical School, Boston, USA / Harvard Pilgrim Health Care Institute, Boston, USA)
  Prof Xiaodong Guan (Peking University Health Science Centre, Beijing, China)
  Dr Xiaoyan Nie (Peking University Health Science Centre, Beijing, China)
  
• Abstract:

  Abstract
  Aims: To investigate the prevalence of longitudinal exposure to multiple drugs with a high level of evidence (Level A) for pharmacogenetic-guided drugs (PGx drugs) among older adults, project the prevalence of pharmacogenes associated with PGx drugs, evaluate the cumulative impact of these gene-drug pairs to health resource utilizations..

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