DDM-013 - Differences in the KATP channel-independent and endothelium-independent effects of pinacidil on bypass grafts from patients with type 2 diabetes mellitus

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: DDM-013
• By: ČAKAR, Uroš (Faculty Of Pharmacy, University Of Belgrade, Serbia)
• Co-author(s): Dr Uroš Čakar (Faculty Of Pharmacy, University Of Belgrade, Belgrade, Serbia)
  Jovana Rajković (Faculty of Medicine, University of Belgrade, Belgrade, Serbia)
  Miloš Gostimirović (Faculty of Medicine, University of Belgrade, Belgrade, Serbia)
  Miodrag Perić (Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia)
  Ana Bukarica (Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia)
  Ljiljana Gojković-Bukarica (Faculty of Medicine, University of Belgrade, Belgrade, Serbia)
  
• Abstract:

  Background: Type 2 diabetes mellitus (T2DM) is one of the main risk factors for cardiovascular complications. The reduced relaxation of blood vessels in diabetic patients may be due to altered expression ∷and/or function of smooth muscle potassium (K) channels. Previously, we have shown that pinacidil, an ATP-sensitive K (KATP) channel opener,..

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