HPS-137 - The effectiveness of establishing a guidance for the off-label use of atropine 1% eye drop in patients with clozapine-induced sialorrhea

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: HPS-137
• By: HUANG, Szu-ying (Taipie City Hospital, SongDe Branch (Taipei City Psychiatric Center), China Taiwan)
• Co-author(s): Ms Szu-ying Huang (Taipie City Hospital, SongDe Branch (Taipei City Psychiatric Center), Taipei, China Taiwan)
  Ms Esther Shin-Feng Shiu (Taipie City Hospital, SongDe Branch (Taipei City Psychiatric Center), Taipei, China Taiwan)
  Mr Chi-Ting Tseng (Taipie City Hospital, SongDe Branch (Taipei City Psychiatric Center), Taipei, China Taiwan)
  
• Abstract:

  Introduction:
  Clozapine, a second-generation antipsychotic, is often used in treating refractory schizophrenia, but 13-48% of patients experience excessive salivation (clozapine-induced sialorrhea, CIS) which can negatively affect clozapine adherence. Recently, off-label use of sublingual atropine 1% eye drop to manage CIS has increased in our..

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