NMS-031 - In-silico and In-vitro investigation of the molecular mechanisms of antiviral compounds for potentially inhibiting Dengue Virus NS2B-NS3 protease.

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: NMS-031
• By: KOTEY, Hassan (University For Development Studies , Ghana)
• Co-author(s): Mr Hassan Kotey (University For Development Studies , Tamale , Ghana / Noguchi Memorial Institute for Medical Research , Accra, Ghana)
  Professor Gideon Helegbe (University For Development Studies , Tamale , Ghana)
  Professor Humphrey Bonney (Noguchi Memorial Institute for Medical Research , Accra, Ghana)
  Professor Samuel Kwofie (West African Center for Cell Biology of Infectious Pathogens (University of Ghana), Accra, Ghana )
  Mr Kiarash Saleki (Babol University of Medical Sciences, Tehran, Iran )
  
• Abstract:

  The recent outlook of Dengue viral infection as a global public health concern, coupled with the reportage of resistance and lack of anti-dengue drugs, calls for a concerted effort to find new leads. The study combined In-silico and in vitro approaches to identify novel potential synthetic small-molecule inhibitors targeting the DENV-2 NS2B-NS3..

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