DDM-017 -Improving the solubility and bioavailability of alpha-lipoic acid via hydroxypropyl-β-cyclodextrin complexation

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: DDM-017
• By: RADIć, Kristina (Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia)
• Co-author(s): Ms Kristina Radić (Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia)
  Karolina Miljak (Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia)
  
• Abstract:

  Alpha-lipoic acid (ALA) exhibits significant therapeutic potential in the management of obesity and its associated comorbidities, including diabetic neuropathy and hyperlipidemia. However, its clinical application is limited by poor oral bioavailability, primarily attributed to its low aqueous solubility and gastrointestinal instability...

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