PPR-166 - Investigating structural features of curcumin-derived CK2 inhibitors for anticancer therapy: A 3D-QSAR, pharmacophore modelling, virtual screening, and molecular docking approach

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: PPR-166
• By: KASHAW, Sushil Kumar (Integrated Drug Discovery Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University Department of Pharmaceutical Sciences, India)
• Co-author(s): Prof Sushil Kumar Kashaw (Integrated Drug Discovery Research Laboratory, Department of Pharmaceutical Sciences, Dr Hari Singh Gour University Department of Pharmaceutical Sciences, Sagar, India)
  
• Abstract:

  Introduction: Casein Kinase 2 (CK2), discovered as one of the earliest protein kinases, is a ubiquitous Ser/Thr protein kinase-specific to acidic environments. CK2 has been implicated in regulating diverse cellular processes and has been linked to the onset of various diseases, including cancer. Method: Consequently, modulating CK2 function has..

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