SAPS-057 - Systematic review of the efficacy and safety of SGLT2 inhibitors in the treatment of type 2 diabetes mellitus

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: SAPS-057
• By: GREKOVA-KAFALOVA, Daniela
• Co-author(s): Assist. prof. Lora Petrova (Faculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", Sofia, Bulgaria)
  Prof. Kalina Andreevska (Faculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", Sofia, Bulgaria)
  Prof Emil Hristov (Faculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", Sofia, Bulgaria)
  Chif assist. prof. Evelina Gavazova (Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria)
  Prof Daniela Grekova-Kafalova (Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria)
  
• Abstract:

  Introduction
  Selective sodium-glucose cotransporter-2 (SGLT2) inhibitors act only at the renal level, allowing the excretion of glucose and acting as osmotic diuretics. By inhibiting the SGLT2 cotransporter, SGLT2 inhibitors avoid glucose reabsorption in the S1 and S2 segments of the proximal tubule. Together with glucosuria, SGLT2 inhibition..

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