DDM-060 - Automated Production of 18F-FDG: Targeted Cyclotron Production and Quality Control Procedures in South Africa

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: DDM-060
• By: SEBATANA, Reabetswe (Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, South Africa)
• Co-author(s): Ms Reabetswe Sebatana (Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa / Department of Nuclear Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa / Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa)
  Sandile Sibiya (Department of Nuclear Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa / Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa / 4Radiochemistry, The South African Nuclear Energy Corporation SOC Ltd., Pelindaba, South Africa)
  Mbongeni Shungube (Department of Nuclear Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa / Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa)
  Motshidisi Ashleigh Mokoena (Department of Nuclear Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa / Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa)
  Nathan Muzamhindo (Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa)
  Louisa Duvenhage (Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa)
  Jan Rijn Zeevaart (Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa / 4Radiochemistry, The South African Nuclear Energy Corporation SOC Ltd., Pelindaba, South Africa)
  Mike Sathekge (Department of Nuclear Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa / Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa)
  Sipho Mdanda (Department of Nuclear Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa / Nuclear Medicine Research Infrastructure, Steve Biko Academic Hospital, Pretoria, South Africa)
  
• Abstract:

  Introduction:
  The expanding field of positron emission tomography (PET) radiopharmaceuticals, particularly fluorine-18-labeled fluorodeoxyglucose ([¹⁸F]F-FDG), is driven by advances in functional imaging and molecular diagnostics. As clinical demand increases, the need for efficient, reproducible production processes and rigorous quality..

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