DDM-012 - Expression and localisation of organic anion transporting polypeptide (Oatp) 2b1 in the term rat placenta

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: DDM-012
• By: NISHIMURA, Tomohiro (Juntendo University, Japan)
• Co-author(s): Dr Tomohiro Nishimura (Juntendo University, Chiba, Japan)
  Ms Sawako Hasegawa (Keio University, Tokyo, Japan)
  Mr Keisuke Orii (Keio University, Tokyo, Japan)
  Dr Saki Noguchi (Keio University, Tokyo, Japan)
  Prof Masatoshi Tomi (Keio University, Tokyo, Japan)
  
• Abstract:

  Introduction: During pregnancy, drugs transfer to the fetus through the placental barrier, which consists of layers of syncytiotrophoblasts (SynT). SynT expresses drug transporters that play a crucial role in the placental transfer of drugs. The structure of SynT varies across species; in humans, it consists of a single layer, whereas in rodents,..

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