PPM-017 - Effects of cyclooxygenase inhibitors on prostaglandin E2 transport in the HK-2 human kidney epithelial cell line

• At: Copenhagen (Denmark) (2025)
• Type: Poster
• Poster code: PPM-017
• By: NAGAI, Junya (Osaka Medical and Pharmaceutical University, Japan)
• Co-author(s): Prof Junya Nagai (Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan)
  Ayaha Koga (Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan)
  Akari Tsuda (Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan)
  Dr Yumiko Urakami-Takebayashi (Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan)
  Prof Yoshio Ohno (Tokyo Medical University, Shinjuku-ku, Tokyo, Japan)
  Dr Hideyuki Motohashi (Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan)
  
• Abstract:

  Background: Enhanced glomerular permeability following hypertension and diabetic nephropathy increases albumin concentration in the renal proximal tubular lumen. Albumin passing through the glomerulus is reported to be involved in the progression of tubulointerstitial damage, leading to end-stage renal disease, but the precise molecular mechanism..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login