Transition temperature microscopy: a novel tool for monitoring drug crystallisation in the stratum corneum

• In: Posters D - Formulation Design and Pharmaceutical Technology
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PD-148
• By: GOH, Choon Fu (School of Pharmacy, University College London, Pharmaceutics, London, United Kingdom)
• Co-author(s): Moffat, Jonathan G. (School of Pharmacy, University College London, London, United Kingdom)
  Jonathan, Hadgraft (School of Pharmacy, University College London, London, United Kingdom)
  Craig, Duncan Q.M. (School of Pharmacy, University College London, London, United Kingdom)
  Lane, Majella E. (School of Pharmacy, University College London, London, United Kingdom)
  
• Abstract:

  Background: Crystallisation of drugs in the stratum corneum (SC) is becoming recognized as one of the factors underlying the poor efficacy of topical preparations. Transition temperature microscopy (TTM) is a localised thermal technique which maps a surface in terms of thermal transitions by combining the high spatial resolution imaging..

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