In vitro studies of the properties of thermosensitive systems prepared on pluronic f-127 as vehicles for methotrexate for delivery to solid tumours

• In: SIG Bioavailability / Bioequivalence - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: BB-P-013
• By: PLUTA, Janusz (Wroclaw Medical University, Wroclaw, Poland)
• Co-author(s): Karolewicz, Bozena (Wroclaw Medical University, WROCLAW, Poland)
  
• Abstract:

  The results of in vitro studies demonstrate that the systems prepared on 14,8% Pluronic F-127 with certain additives, i.e. lactose, glucose, propylene glycol, glycerol may be used as vehicles for active substance administered as direct injection into the neoplastic tumour. Prepare the sol-gel transition temperature of the prepared formulations at..

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