Design and evaluation of mucoadhesive microspheres of amphotericin b

• In: Posters D - Formulation Design and Pharmaceutical Technology
• At: PSWC, Melbourne (Australia) (2014)
• Type: Poster
• Poster code: PD-006
• By: JAIN, Prateek (Manipal College of Pharmaceutical Sciences, Manipal University, Pharmaceutical Biotechnology, Manipal, karnataka, India)
• Co-author(s): Lekhadia, Smeet (Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, karnataka, India)
  Vanathi, Meenashi (Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, karnataka, India)
  Udupa, Nayanabhirama (Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, karnataka, India)
  Rao, Venkata J (Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, karnataka, India)
  Sivagurunathan, N (Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, karnataka, India)
  
• Abstract:

  Background
  Amphotericin B is used intravenously for systemic fungal infections but poses potentially lethal side-effects like acute reactions, chills, anorexia, hypotension, multiple organ damage, nephrotoxicity, etc. Therefore, it is required to deliver amphoteracin B through an oral route. But, the problem associated with the oral use of..

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