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Glucose clearance is a reliable indicator of insulin resistance in spontaneously diabetic goto-kakizaki rats and wistar rats fed with a high-sucrose high-fat diet

  • In: SIG Bioavailability / Bioequivalence - Poster Session
  • At: Salvadore (Brazil) (2006)
  • Type: Poster
  • Poster code: BB-P-005
  • By: SATO, Shinji (Niigata Univ. of Pharm. & Appl. Life Sci, Niigata, Japan)
  • Co-author(s): Konishi, Testuya (Niigata Univ. of Pharm. & Appl. Life Sci, NIIGATA, Japan)
    Takeishi, Kinji (BOURBON Corporation, KASHIWAZAKI, Japan)
    Maejima, Daisuke (BOURBON Corporation, KASHIWAZAKI, Japan)
    Mineo, Shigeru (BOURBON Corporation, KASHIWAZAKI, Japan)
  • Abstract:

    Aims: The postprandial hyperinsulinemia is a causative factor of obesity, pancreatic beta-cell exhaustion and the development of diabetes. The insulin resistance in peripheral tissues characterizes the metabolic syndromes. The insulin resistance is measured by the glucose clamp technique. Although this glucose clamp method is very high sensitive..

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Last update 28 September 2023

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