Towards biorelevant flow-through dissolution method for nimesulide immediate-release tablets: In vitro-in silico approach

• In: SIG Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: FDP-P-08
• By: GRBIC, Sandra (Faculty of Pharmacy, University of Belgrade, Dept. of Pharmaceutical Technology and Cosmetology, Belgrade, Serbia)
• Co-author(s): Panzalovic, B. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
  Markovic, L. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
  Parojcic, J. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
  Djuric, Z. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
  
• Abstract:

  With the right choice of experimental conditions, dissolution test might be used to evaluate drug in vivo performance, thus serving as a surrogate for clinical studies. The objective of this study was to investigate the applicability of a flow-through dissolution apparatus to in vitro assess biopharmaceutical properties of nimesulide

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