Stability of insulin in plga nanoparticles after complexation with protamine

• In: SIG Pharmaceutical Biotechnology - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: PB-P-001
• By: CHEN, Yan (Curtin University of Technology, School of Pharmcy, Perth, Australia)
• Co-author(s): Wang (Curtin University of Technology, PERTH, Australia)
  Benson (Curtin University of Technology, PERTH, Australia)
  
• Abstract:

  Aims: To investigate the effect of complexation on the stability of insulin in biodegradable nanoparticles of poly (D, L-lactic-co-glycolic acid) (PLGA). Methods: Bovine insulin was incorporated into PLGA nanoparticles by a solvent evaporation and a solvent diffusion method following its complexation with protamine. A stability-indicating high..

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