In-line monitoring of a continuous blending process by NIR

• In: 8F1 - From development to marketing - short oral communications on Saturday, 6 October 2012, 12:15-13:45
• At: Amsterdam (the Netherlands) (2012)
• Type: Presentations + Posters
• By: MARTINEZ, Lizbeth (University of Basel, Pharmaceutical Sciences, Basel, Switzerland)
• Co-author(s): Liesum, L.M. (Novartis Pharma AG, Basel, Switzerland)
  Peinado, A. (Novartis Pharma AG, Basel, Switzerland)
  Betz, G. (University of Basel, Basel, Switzerland)
  
• Abstract:

  One approach to assess the homogeneity of a continuous blending process is by retrieving samples at the outlet of the blender followed by an off-line method. This methodology reduces the number of samples that can be analyzed and does not allow a fast reaction in case of a problem. On the view of the PAT initiative from the FDA, continuous

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