Multifunctional envelope-type nano device for in vivo systemic delivery of siRNA

• In: S4 - Targeted drug delivery: From Concept to Clinical reality on Tuesday, 2 September 2008, 14:00-17:00
• At: Basel (Switzerland) (2008)
• Type: Presentation
• By: HARASHIMA, Hideyoshi (Hokkaido University, Sapporo, Japan)
• Abstract:

  We recently proposed a novel non-viral gene delivery system multifunctional envelope-type nano device (MEND) to realize Programmed Packaging. The ideal MEND consists of a condensed DNA core and a lipid envelope structure equipped with the various functional devices. The compacted core has some advantages, such as the protection of DNA from DNase,

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