Determination of omeprazole, lanzoprazole and pantoprazole in presence of their acid- induced degradation products using derivative- ratio spectrophotometry and partial least squares methods.

• In: SIG Quality of Pharmaceuticals - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: QP-P-009
• By: WAHBI, Abdelaziz (University of Alexandria, Pharm. Analytical Chemistry, Alexandria, Egypt)
• Co-author(s): Fahmy (University of Alexandria, ALEXANDRIA, Egypt)
  Moneeb (University of Alexandria, ALEXANDRIA, Egypt)
  
• Abstract:

  Omeprazole I, lansoprazole II, and pantoprazole III, have been determined trically in presence of their acid-induced degradation products using (i) first and second order-derivative ratios and (ii) PLS applied to absorbance and absorbance ratio data. Laboratory prepared mixtures of the intact compounds with the corresponding acid induced..

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