Gene transfer system into human placental cells by fiber-modified adenovirus vectors

• In: SIG Pharmaceutical Biotechnology - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: PB-P-004*
• By: WATANABE, Yoshiteru (Showa Pharmaceutical University, Pharmaceutics and Biopharmaceutics, Tokyo, Japan)
• Co-author(s): Koizumi (Showa Pharmaceutical University, TOKYO, Japan)
  Kondoh (Showa Pharmaceutical University, TOKYO, Japan)
  Fujii (Showa Pharmaceutical University, TOKYO, Japan)
  Mizuguchi (National Institute of Health Sciences, OSAKA, Japan)
  Hayakawa (National Institute of Health Sciences, TOKYO, Japan)
  Nakanishi, Tsuyoshi (Osaka University, OSAKA, Japan)
  Tanaka, Keiichi (Osaka University, OSAKA, Japan)
  
• Abstract:

  [Purpose] Aim of this study was evaluate the ability of fiber-modified adenovirus (Ad) vectors, which can be effective in cells lacking the coxsackievirus and adenovirus receptor (CAR), to transduce human trophoblast cell lines used as in vitro models of human placenta.
  
  [Methods] Human trophoblast cell lines, JEG-3, JAR and BeWo cells were..

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