Synthesis and antitumor activity of anilinoquinoline derivatives

• In: Medicinal Chemistry Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: MC-P-005
• By: YANG, Shyh-Chyun (School of Pharmacy, Kaohsiung Medical University, Kaohsiung, China Taiwan)
• Co-author(s): Peng, Huang-Kai (School of Pharmacy, Kaohsiung Medical University, KAOHSIUNG, China Taiwan)
  Wang, Li-Ya (School of Pharmacy, Kaohsiung Medical University, KAOHSIUNG, China Taiwan)
  Chang, Jan-Gowth (Department of Medical Research, Kaohsiung Medical University, KAOHSIUNG, China Taiwan)
  
• Abstract:

  Studies indicated that quinoline derivatives, the bicyclic heteroaromatic pharmacophore, had diverse biologically activies. In our study, we have synthesize and investigated the antiproliferative and apoptotic effects of anilinoquinoline derivatives on human hepatocellular carcinoma cells (Huh-7). We have found that anilinoquinoline derivatives..

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