Effect of dietary fat on the oral bioavailability of itraconazole in healthy volunteers

• In: SIG: Bioavailability/Bioequivalence - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: BB-P-017
• By: KIM, Chong-Kook (Seoul National University, Seoul, South-Korea)
• Co-author(s): Yun-Kyoung, Song (Seoul National University, SEOUL, South-Korea)
  Mal-Sook, Jang (Seoul National University, SEOUL, South-Korea)
  
• Abstract:

  Itraconazole is an orally active antifungal agent, and its oral bioavailability is affected food intake. The present study was undertaken to investigate the effect of dietary fat on the itraconazole absorption from Sporanox® capsule in healthy volunteers. Eight subjects received a Sporanox® capsule (itraconazole 100 mg) in the fasted state,..

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