Platelet responsiveness and platelet-leukocyte aggregate formation under conditions of hypothermia

• In: Hospital Pharmacy - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: HPS-P-090
• By: KARIYAZONO, Hiroko (Nagasaki International University, Sasebo, Japan)
• Co-author(s): Ayukawa, Osamu (Kagoshima University, Japan)
  Nakamura, Kazuo (Nihon Pharmaceutical University, Japan)
  Ikeda, Ryuji (Kagoshima University, Japan)
  Arima, Junko (Kagoshima University, Japan)
  Shinkawa, Terutoshi (Kagoshima University, Japan)
  Sakata, Ryuzo (Kagoshima University, Japan)
  Yamada, Katsushi (Kagoshima University, Japan)
  
• Abstract:

  BACKGROUND: It is well known that human platelet function and viability are affected by the condition of storage temperature of collected blood. Hypothermic storage of blood causes cold-induced activation of platelets. Chilling platelets to 20?C causes marked shape change from discoid to spherical with multiple filopodia, releases ?-granule..

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