NOVEL PEPTIDE-BASED NANOVESICULAR FORMULATION OF AN ANTIPSYCHOTIC AGENT FOR TRANSDERMAL DELIVERY

• At: AbuDhabi (United Arab Emirates) (2019)
• Type: Poster
• Poster code: POS-FDP-018
• By: MANIKKATH, Jyothsna (Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Pharmaceutics, India)
• Co-author(s): Jyothsna Manikkath: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India
  Srinivas Mutalik: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India
  
• Abstract:

  Background

  Asenapine maleate (ASP) is an atypical antipsychotic used clinically in the treatment of schizophrena and bipolar disorder. It is extensively metabolized in the liver, yielding an oral bioavailability of <2%.

  Methods

  Liposomes were prepared thin film hydration technique, followed by ultrasound-assisted size reduction. Fractional Factorial
  ..

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