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Functional influx of Taurine and MPP+ is upregulated in HEK cells grown in Transwell filters compared to stiff plastic wells

  • In: Poster Presentation
  • At: Stockholm (Sweden) (2017)
  • Type: Poster
  • Poster code: P-B-056-Tuesday
  • By: STEFFANSEN, Bente (University of Southern Denmark, Department of Chemistry, Physics and Pharmacy, Odense, Denmark)
  • Co-author(s): Janni Støvring Mortensen: Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark
    Bente Gammelgaard: Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark
    Roos Masereeuw: Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands
    Bente Steffansen: Department of Chemistry, Physics and Pharmacy, University of Southern Denmark, Odense, Denmark
  • Abstract:

    Backgrounds

    The human embryonic kidney (HEK-293) cells seem to loose their phenoltypical characteristics such as their expression of many membrane transporters when cultured conventionally on the top of stiff plastic wells under static conditions (SC). Grown under these conventional conditions, HEK-293 cells perform a poor model for studying..

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Last update 28 September 2023

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