Synthesis and Evaluation of New Quinoline-Based Thiazole Derivatives as Potent Anticancer Agents

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-002-Monday
• By: ALTıNTOP, Mehlika Dilek (Anadolu University Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir, Turkey)
• Co-author(s): Mehlika Dilek Altıntop: Department of Pharmaceutical Chemistry, Anadolu University Faculty of Pharmacy, Eskişehir, Turkey
  Ali Ergüç: Department of Pharmaceutical Toxicology, Ege University Faculty of Pharmacy , İzmir, Turkey
  Belgin Sever: Department of Pharmaceutical Chemistry, Anadolu University Faculty of Pharmacy, Eskişehir, Turkey
  Özlem Atlı: Department of Pharmaceutical Toxicology, Anadolu University Faculty of Pharmacy, Eskişehir, Turkey
  
• Abstract:

  Backgrounds

  The clinical efficacy of tiazofurin, bleomycins and dasatinib has pointed out the importance of thiazole scaffold in the field of cancer research. On the other hand, quinoline scaffold plays an important role in anticancer drug development. Bosutinib, lenvatinib and cabozantinib, protein kinase inhibitors, are quinoline-based anticancer

  ..

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