PREPARATION AND CHARACTERIZATION OF AVANAFIL NANOCRYSTALS

• In: Poster Session
• At: Düsseldorf (Germany) (2015)
• Type: Poster
• By: ABOUBAKR, Karim (Faculty of pharmacy, Cairo university, Cairo, Egypt)
• Co-author(s): Karim Aboubakr
  
• Abstract:

  Avanafil is a recently EMA-approved PDE5 inhibitor used for treatment of erectile dysfunction.

  Combined bottom-up and top-down techniques were used for preparation of 18 nanocrystal formulas in 3².2¹ full factorial design, where solutions of the drug in dimethylsulphoxide were crystallized by abrupt addition of water as a counter-solvent, then the

  ..

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