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Determination of ampicillin in human plasma by lc-ms/ms and comparative bioavailability of two ampicillin formulations.

  • In: SIG Bioavailability / Bioequivalence - Poster Session
  • At: Salvadore (Brazil) (2006)
  • Type: Poster
  • Poster code: BB-P-018
  • By: PEREIRA DE SANTANA, Davi (UFPE, Recife, Brazil)
  • Co-author(s): Mota Gonçalves, Talita (UFPE, RECIFE, Brazil)
    Cesar Galindo Bedor, Danilo (UFPE, RECIFE, Brazil)
    Pires de Abreu, Luis Renato (UFPE, RECIFE, Brazil)
    Eduardo Miranda de Souza, Carlos (UFPE, RECIFE, Brazil)
    Galindo Paes de Lira, Ricardo (UFPE, RECIFE, Brazil)
    Cristina de Souza, Vanessa (UFPE, RECIFE, Brazil)
  • Abstract:

    A simple, fast and selective LC-MS/MS method was described for the determination of ampicillin in human plasma using amoxicillin as internal standard. The samples were prepared from human plasma by solid-phase extraction (SPE), and the analytes were determined using electrospray positive ionization (ES+) in the multiple reaction monitoring mode..

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Last update 28 September 2023

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