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Rage, receptor of advanced glycation endoproducts, negatively regulates chondrocytes differentiation.

  • In: Posters: Drug Design and Discovery
  • At: Bangkok (Thailand) (2014)
  • Type: Poster
  • Poster code: POS-DDD002
  • By: FUJITA, Takashi (Ritsumeikan Univ., Pharmaceutical Sciences, Kusatsu, Japan)
  • Abstract:

    RAGE, receptor for advanced glycation endoproducts (AGE), has been characterized as an activator of osteoclastgenesis, while it was not clear whether RAGE directly regulate chondrocytes proliferation and differentiation or not. Here, we showed that RAGE has an inhibitory role for chondrocytes differentiation. RAGE expression was observed in..

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Last update 28 September 2023

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