Enhanced bioavailability of poorly water-soluble clotrimazole by inclusion with ?-cyclodextrin

• In: Industrial Pharmacy Section - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: IPS-P-028
• By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, South-Korea)
• Co-author(s): Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Kwak, Mi-Kyoung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Yoo, Bong-Kyu (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Kim, Jung-Ae (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Lyoo, Won Seok (School of Textiles, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Newa, Madhuri (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Bhandari, Krishna Hari (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Balakrishnan, Prabagar (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Xuan, Jing-Ji (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Li, Dong-Xun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Piao, Ming-Guan (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  
• Abstract:

  Purpose: The aim of the study was to investigate the enhanced solubility, dissolution and bioavailability of clotrimazole by inclusion complex with ß-cyclodextrin. Method: In different molar ratios clotrimazole and ß- CD were dissolved in ethanol and water, respectively, and mixed together to obtain clear solution. The resulting solutions were..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login