Polymer-functionalised silica lipid hybrid materials that enhance the solubilization and oral absorption of poorly water soluble drugs

• In: DDA SUBMITTED ORALS on Wednesday, 16 April 2014, 16:30-18:00
• At: PSWC, Melbourne (Australia) (2014)
• Type: Presentation
• By: PRESTIDGE, Clive (University of South Australia, The Wark, Mawson lakes, Australia)
• Co-author(s): Rao, Shasha (University of South Australia, Mawson lakes, Australia)
  Richter, Katharina (University of South Australia, Mawson lakes, Australia)
  Tan, Angel (University of South Australia, Mawson lakes, Australia)
  
• Abstract:

  Background and Aims: Silica lipid hybrid (SLH) microparticles synergistically utilise the features of porous silica and digestible lipids in overcoming the oral delivery challenges associated with BCS type 2 drugs. This study focused on the incorporation of polymeric excipients into SLH particles with the aim of controlling drug release and lipid

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