Development of transparent ibuprofen-loaded solution with enhanced oral bioavailability using poloxamer 188 and menthol

• In: Industrial Pharmacy Section - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: IPS-P-009
• By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, South-Korea)
• Co-author(s): Piao, Ming-Guan (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Li, Dong-Xun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Xuan, Jing-Ji (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Choi, Han-Gon (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Kwak, Mi-Kyoung (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Rhee, Jong-Dal (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Yoo, Bong-Kyu (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Kim, Jung-Ae (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Lyoo, Won Seok (School of Textiles, Yeungnam University, GYEONGSAN-SI, South-Korea)
  
• Abstract:

  Purpose. To develop transparent ibuprofen-loaded solution with the enhanced oral bioavailability using poloxamer and menthol. Method. The effects of menthol and poloxamer 188 on the aqueous solubility of ibuprofen were investigated. The dissolution and pharmacokinetic study of ibuprofen delivered by the poloxamer gels composed of poloxamer 188 and ..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login