Effect of chitosan molecular weight on drug release from directly compressed alginate-chitosan matrices

• In: SIG Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: FDP-P-53
• By: CALIJA, Bojan (Faculty of Pharmacy, University of Belgrade, Department of Pharmaceutical Technology and Cosmetology, Belgrade, Serbia)
• Co-author(s): Djuris, J. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
  Cekic, N. (Faculty of Tecnhology, University of Nis, Leskovac, Serbia)
  Radulovic, Z. (R&D Institute, Galenika, Belgrade, Serbia)
  Milic, J. (Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia)
  
• Abstract:

  
  Aims
  . The aim of the presented work was to evaluate the effect of sodium alginate (SA)/chitosan (CH) ratio and CH molecular weight on drug release and swelling kinetics of SA-CH directly compressed matrices.
  Methods
  . Matrices containing 200 mg of naproxen were prepared by direct compression of mixtures of the drug, SA and one of the following types

  ..

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