In vitro ADME studies

• In: S3 - Improving bioavailability/bioequivalence on Tuesday, 4 September 2007, 9:00-12:00
• At: Beijing (China) (2007)
• Type: Presentation
• By: YAMASHITA, Shinji (Setsunan University, Osaka, Japan)
• Abstract:

  Permeability and solubility of drugs are considered to be the most important factors to determine oral drug absorption. Caco-2 cell monolayer system is now widely used in the pharmaceutical industries to screen the membrane permeability of new drug-candidates. Also, their water-solubility is measured in vitro at the early stage of drug

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