Complexation of celecoxib and meloxicam with 2-hydroxy propyl beta-cyclodextrin using different techniques

• In: Industrial Pharmacy Section - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: IPS-P-004
• By: KAMEL, Ola (Amriya, Research and product development, Alexandria, Egypt)
• Co-author(s): Mortada (Faculty of Pharmacy, ALEXANDRIA, Egypt)
  El Maradny (Faculty of Pharmacy, ALEXANDRIA, Egypt)
  Hikal (Amriya, ALEXANDRIA, Egypt)
  
• Abstract:

  The effect of hydroxypropyl ß-cyclodextrin (HPB) on the aqueous solubility and dissolution of celecoxib and meloxicam was investigated. Solid complexes were prepared by freeze drying, evaporation, and kneading. Various ratios of drug to HPB were prepared ranging from 1:1 up to 1:10. The resulting complexes were characterized using differential..

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