Ursolic acid induces human hepatoma cell line smmc-7721 apoptosis via p53-dependent pathway

• In: Natural Products Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: NP-P-001
• By: YU, Yan-Xia (Suzhou Municipal Hospital, Suzhou, China)
• Co-author(s): Gu, Zhen-Lun (Soochow Institute of Chinese Materia Medica, Suzhou, China)
  Yin, Jiang-Lin (Suzhou Municipal Hospital, Suzhou, China)
  Chou, Wen-Hsien (Soochow Institute of Chinese Materia Medica, Suzhou, China)
  Kwok, Chi-Yi (Soochow Institute of Chinese Materia Medica, Suzhou, China)
  Qin, Zheng-Hong (Soochow University School of Medicine, Suzhou, China)
  Liang, Zhong-Qin (Soochow University School of Medicine, Suzhou, China)
  
• Abstract:

  Background : Ursolic acid (UA) is ubiquitous in the plant kingdom. Although UA has been shown to inhibit the proliferation of liver cancer cells and it can induce apoptosis of many tumor cells, the molecular mechanism of its anti-hepatoma is still not well defined. The objective of this study was to investigate the inhibitory effect and mechanisms

  ..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login