Development and validation of a new HPLC method with fluorometric detection for analysis of furosemide in samples for liver perfusion studies

• In: Biopharmaceutics Classification System - Posters
• At: Istanbul (Turkey) (2009)
• Type: Poster
• Poster code: BCS-P-003
• By: KAYNAK, Mustafa Sinan (Hacettepe University, Faculty of Pharmacy, Dept. of Pharmaceutical Technology, Ankara, Turkey)
• Co-author(s): Sahin, Selma (Hacettepe University, Faculty of Pharmacy, Dept. of Pharmaceutical Technology, ANKARA, Turkey)
  
• Abstract:

  Furosemide is a loop diuretic used to treat excessive fluid accumulation and swelling (edema) of the body caused by heart failure, cirrhosis, chronic kidney failure, and nephrotic syndrome. Like other loop diuretics, furosemide acts by inhibiting the Na-K-2Cl symporter in the thick ascending limb of the loop of Henle [1, 2]. The aim of this study

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