Optimization of a modified quasi-emulsion solvent diffusion method for the preparation of directly compressible ibuprofen spheres

• In: Industrial Pharmacy- Posters
• At: Istanbul (Turkey) (2009)
• Type: Poster
• Poster code: IPS-P-002
• By: ELFAHAM, Tahani Hassan (Faculty of Faculty - Assiut university, Assiut, Egypt)
• Co-author(s): Ibrahim1, Said (Faculty of Faculty - Assiut university, Assiut, Egypt)
  Helmy, Abdel Rahman (Departement of research and development, CID Co, Assiut Factory, Assiut, Assiut, Egypt)
  
• Abstract:

  In a previous study(1), a modified QESD technique was applied successfully to improve the poor flowability, compressibility and dissolution properties of ibuprofen (class II drug). Different polymers (PVP, HPMC, PEG 4000) and/or surfactants (Tween 80 and Myrj 53)were used to obtain spheres of optimum size (300-600 µm) and improved dissolution

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