The biological significance of the high phosphorylation of scs-binding proteins involved in the regulation of neuronal signal transduction

• In: Clinical Biology - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: CBS-P-005
• By: OHTSUKI, Kenzo (Kitasato University, Graduate School of Medical Sciences, Sagamihara, Japan)
• Co-author(s): Kawakami, Fumitaka (Kitasato University, Graduate School of Medical Sciences, SAGAMIHARA, Japan)
  Suzuki, Kanzo (Kitasato University, Graduate School of Medical Sciences, SAGAMIHARA, Japan)
  Furuya, Teisuke (Kitasato University, Graduate School of Medical Sciences, SAGAMIHARA, Japan)
  
• Abstract:

  [Purpose] Recently, we reported that, in the presence of sulfatide and holesterol-3-sulfate (SCS), casein kinase 1 (CK1) highly phosphorylates SCS-binding proteins (SCS-BPs: myelin basic protein, FGF-binding protein and HMG1) containing novel consensus phosphorylation motifs [K/R-X-K/R-X-X-S/T] for CK1 in vitro [Biol. Pharm. Bull., 31, 193-200..

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