The Effect of Methotrexate on the Absorption of Tetrahydrobiopterin in Rats

• In: Clinical Biology Section - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: CBS-P-016
• By: LIN, Chia-chun (School of pharmacy, National Taiwan Uni, TAIPEI, China Taiwan)
• Co-author(s): Ho, Yunn-Fang (School of pharmacy, National Taiwan Uni, TAIPEI, China Taiwan)
  
• Abstract:

  Tetrahydrobiopterin (5,6,7,8-tetrahydropterin, BH4) is an endogenous cofactor in human body and has many important functions. It has been reported that the absorption mechanisms of BH4 in intestine and liver are different, i.e. by direct uptake in intestine and indirect mechanism in the liver. The intestinal mucosa might be able to take up BH4..

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