A High-resolution Method to Assess Cell Multinucleation Using Cytoplasm-localized Fluorescent Probes (CLFP)

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-026-Tuesday
• By: HUI, Wen (Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College, Bei Jing, China)
• Co-author(s): Wen Hui: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  Cui huaqing: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  Xi meiyang: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  Xiao qiong: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  Zhang xiang: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  Wang xiaojian: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  Yin dali: State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Bei Jing, China
  
• Abstract:

  Backgrounds

  Multinucleated cells have been observed in many diseases including cancer, which is closely related to chromosomal instability although the precise mechanisms remain unclear. Nuclear staining dyes, such as, Giemsa and DAPI, are often used to stain cell nuclei to display the morphologies of cell multinucleation. However, owing to the..

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