Study on skin metabolism of ketoprofen ethyl ester in various species

• In: Miscellaneous - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: M-P-049
• By: ZHU, Quan-Gang (Changhai hospital, Shanghai, China)
• Co-author(s): HU, Jin-Hong (Changhai hospital, SHANGHAI, China)
  LIU, Ji-Yong (Changhai hospital, SHANGHAI, China)
  GAO, Li-Hong (Changhai hospital, SHANGHAI, China)
  
• Abstract:

  Objectvie: This study was performed to compare the difference of skin metabolism of ketoprofen ethyl ester in various species. Methods: In vitro skin hydrolysis experiments using skin homogenates were carried out. Metabolite formation rate was determined and compared among New Zealand rabbit, Weanling domestic pig, Sprague-Dawley rat and human...

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