The effect of MDR1 polymorphisms on cyclosporine a pharmacokinetics in Chinese renal transplant patients

• In: SIG Individualised Medicine - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: IM-P-010
• By: QIU, Xiaoyan (Huashan hospital, Shanghai, China)
• Co-author(s): Jiao, zheng (Huashan hospital, SHANGHAI, China)
  Zhong, longjin (Huashan hospital, SHANGHAI, China)
  Zhang, ming (Huashan hospital, SHANGHAI, China)
  Ying, yinqing (Shanghai municipal health school, SHANGHAI, China)
  
• Abstract:

  OBJECTIVE To evaluate retrospectively the effects of genetic polymorphisms in exon 12 C1236T, exon 21 G2677T/A and exon 26 C3435T of MDR1 on CsA pharmacokinetics in Chinese renal adult transplant patients within the first month post-operation. METHODS 89 de novo renal transplant recipients receiving CsA were genotyped by polymerase chain reaction

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