Effect of formulation and route of administration on the bioavailability of recombinant hirudin

• In: G37 - Manufacturing and good manufacturing practice IPS (part 1) on Wednesday, 5 September 2007, 9:00-11:45
• At: Beijing (China) (2007)
• Type: Presentations + Posters
• By: LIU, Yu (Peking University, Beijing, China)
• Co-author(s): Zhang, Qiang (Peking University, Beijing, China)
  
• Abstract:

  The objective of our research was to study the effect of formulation and route of administration on the bioavailability of recombinant hirudin variant-2 (rHV2). Pharmacokinetics and pharmacodynamics of recombinant hirudin variant-2 (rHV2) which is an antithrombotic polypeptide were compared for four non-parenteral administration routes,

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