Validation of HPLC and UV spectrophotometry determinations of cefixime in capsules

• In: SIG Quality of Pharmaceuticals - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: QP-P-013
• By: BITTENCOURT, Michele (Univ. de Pelotas & da Campanha, Pelotas City & BagÉ City, Brazil)
• Co-author(s): Sippel, Juliana (Universidade Federal do Rio Grande do Su, PORTO ALEGRE, Brazil)
  Steppe, Martin (Universidade Federal do Rio Grande do Su, PORTO ALEGRE, Brazil)
  Schapoval, Elfrides (Universidade Federal do Rio Grande do Su, PORTO ALEGRE, Brazil)
  
• Abstract:

  In this study two different methods, HPLC and UV spectrophotometry, are presented and validated for the determination of cefixime in capsules, a known antibiotic, with excellent efficacy in the treatment of urinary and respiratory infections. Cefixime was determined by HPLC method using a LiChrospher 100 RP-18 (5mm) column with mobile phase

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