BLOCKING THE L-TYPE CA2+ CHANNELS (CAV1.2) IS THE KEY MECHANISM FOR THE VASCULAR RELAXING EFFECT OF PTERODON SPP. AND ITS ISOLATED DITERPENE METHYL-6Α-ACETOXY-7Β-HYDROXYVOUACAPAN-17Β-OATE

• In: Poster Session
• At: Düsseldorf (Germany) (2015)
• Type: Poster
• By: ROCHA, Matheus (Federal university of Goias, Pharmacology, Goiânia, Brazil)
• Co-author(s): Matheus lavorenti Rocha
  
• Abstract:

  Pterodon pubescens Benth and Pterodon emarginatus Vogel, popularly known as “sucupira”, has ethnopharmacological application which is described as having antispasmodic and relaxant effects. Hence, it was hypothesized that sucupira oil-resin (SOR) could induce smooth muscle relaxation.

  Vascular reactivity experiments were performed using rat aortas

  ..

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